A few months ago I had a conversation with clinician Annette Norris about anxiety. That was a very timely conversation as many were feeling very anxious as the pandemic began to develop and isolate us. I’ve recently noticed more sadness and depression in people I interact with. I thought it might be a good idea to have a conversation about sadness with Annette again and see if we can’t get some more useful clinical insights. I learned a lot from Annette. I hope you do too!